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ScienceDaily (Aug. 31, 2012) ? Scientists at the research centre MEMBRANES at Aarhus University, Denmark, have completed an old puzzle, which since the 1960s from many sides has been regarded as impossible to complete. The challenge was to solve the structure of the protecting protein complex that forms when hemoglobin is released from red cells and becomes toxic. This toxic release of hemoglobin occurs in many diseases affecting red cell stability, e.g. malaria.
Technically, the most important finding in this report in Nature is a high-resolution three-dimensional mapping of the so-called 'haptoglobin-hemoglobin complex'.
"After many failing experiments, our breakthrough came when we gave up using human material and went to the local slaughterhouse to purchase pig blood. Not a particular high-technological approach, but this transition from studying human blood to blood from a species with close homology had magic effects. After running into dead ends for two years and trying out the most complex gene-technological ways to produce the right material, it suddenly worked," says S?ren Kragh Moestrup, the head of the research group at Department of Biomedicine.
The discovery provides new essential information on hemoglobin that makes up most of the red cell interior. hemoglobin is an essential blood component for transport of oxygen, but it becomes toxic with potential damaging effects on tissues, in particular the kidneys, when it is released from the red cells. An excessive release can occur in many diseases, such as malaria and other infections.
However, the body has a sophisticated defence system. The first line defence is carried out by the blood protein haptoglobin, which captures hemoglobin and gates it to a receptor that engulfs the hemoglobin-haptoglobin complex. This function of the receptor named CD163 was originally discovered by the same group.
"We have now shown how this unique protein complex forms by generation of a detailed 3-dimensional map of each atom. This shows for the first time how the complex is formed and explains the tight protein association," says PhD Christian Brix Folsted Andersen. He has together with Master's student Morten Torvund-Jensen been an essential driving force in the project.
The results have also led to an unexpected discovery of a novel type of protein structure and a new patent submission on exploitation of the discovery for use in generation of a new type of synthetic proteins to be used in therapy and diagnostics.
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The above story is reprinted from materials provided by Aarhus University, via EurekAlert!, a service of AAAS.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/Whb_085p13s/120831104155.htm
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By Lucia Mutikani, Reuters
WASHINGTON -- The U.S. economy continued to grow gradually in July and early August, but manufacturing activity was softening in many areas of the country, the Federal Reserve said on Wednesday.
In its Beige Book report of anecdotal information on business activity collected from contacts nationwide, the U.S. central bank said retail activity, including auto sales, had picked up since the last report.
"Reports from the twelve Federal Reserve districts suggest economic activity continued to expand gradually in July and early August across most regions and sectors," the Beige Book said.
The economic snapshot was prepared for use by Fed officials at their upcoming policy meeting on Sept. 12-13, when policymakers will debate whether further central bank bond purchases are warranted to spark a stronger recovery.
The economy grew at a 1.7 percent annual rate in the second quarter, supported by exports and investment in the construction of nonresidential structures. The pace was a slowdown from the 2.0 percent rate set in the first quarter.
The Beige Book captured the beginning of the third quarter and suggested the speed of the recovery was falling short of what was needed to spur faster hiring. "Most districts reported that employment was holding steady or growing only slightly," the Fed said.
It also noted that manufacturing was softening in many districts, matching findings from recent regional factory surveys. Much of the slowdown is blamed on weak demand overseas, especially in Asia.
"Many districts reported some softening in manufacturing, either a slowdown in the rate of growth or a decline in the level of sales, output or orders," the Fed said. "Across the districts, few manufacturing firms reported any major hiring or layoffs."
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The simplest way for individual investors to achieve adequate international diversification is through an ETF. The iShares MSCI World Index Fund will give investors sufficient global diversification, with a decent dividend to boot. For investors looking for a more hands-on approach, below are three Argentinian companies that might be suitable for a more globally diversified portfolio.
Arcos Dorados (NYSE: ARCO), which means ?Golden Arches? in Spanish, is a restaurant owner-operator in Latin America. Described as the McDonald?s (NYSE: MCD) of Latin America (very accurate description), Arcos Dorados acquired McDonald?s Latin American operations in 2007. This acquisition gave Arcos Dorados the exclusive rights to franchise McDonald?s restaurants in South America, Central America and the Caribbean. In the 20 countries Arcos Dorados operates in, there are about 580 million people, but only 1,858 McDonald?s restaurants. That equates to one McDonald?s restaurant for every 312,163 people in Latin America. If you contrast that to McDonald?s US-only operations, there about 312 million Americans being served by 14,098 McDonald?s restaurants. That equates to one McDonald?s restaurants for every 22,130 Americans. Quite a large difference between the two regions. There is huge growth potential for Arcos Dorados in Latin America.
McDonald?s and Arcos Dorados are the undisputed leader in Latin America. When it comes to competition from Yum! Brands (NYSE: YUM) and other major global restaurant companies. There are more McDonald?s restaurants than its next five largest competitors combined. Yum! Brands, for example, has little exposure to Latin America as it concentrates its efforts primarily on Chile. While that Chinese growth strategy has been very good for Yum! Brands, it has left McDonald?s and Arcos Dorados with the clear-cut first-mover advantage in Latin America.
MercadoLibre (NASDAQ: MELI), which means ?free market? in Spanish, is an ecommerce company Latin America. The company is primarily known for its online auction website. Because of the very similar businesses, MercadoLibre is often referred to as the eBay (NASDAQ: EBAY) of Latin America. This is not only because its businesses are similar, but also because eBay is a global partner and an 18% stakeholder in MercadoLibre.
Like with eBay, the story here is not MercadoLibre?s online auction website. The real story and growth potential is its ecommerce solutions and online payment businesses. MercadoShops (MercadoLibre?s version of eBay?s GSI Commerce) is the company?s ecommerce solutions division. MercadoShops creates online shopping websites for small and medium sized businesses, as well as marketing those websites and integrating those sites into social networks. MercadoPago (MercadoLibre?s version of eBay?s PayPal) is the company?s online payment system, allowing users to safely and securely transact online.
MercadoLibre is the hands-down leader in Latin American online retail. eBay attempted to break into the market years ago, but failed to take significant marketshare away from MercadoLibre. In the end eBay settled for a partnership with and an investment in MercadoLibre?s business. Amazon recently announced that it would try its hand at Latin America. While Amazon?s entry could put pressure on MercadoLibre, it is not guaranteed that Amazon?s luck will be any better than eBay?s. Amazon would not be the first American powerhouse to fail to gain traction in Latin America. MercadoLibre has the advantage of age (13 years in business), an understanding of Latin American retail culture and a payment system (MercadoPago) that is trusted by consumers. These?are not an easy things to overcome.
Cresud is an agriculture powerhouse in South America. The company manages 34 South American farms comprising about one million total hectares of land. Their land usage production includes crops, beef cattle, milking cows and animal feed. In addition to managing its existing farm land, the company continues to look for attractive acquisitions. Cresud also has many investments in other companies. Cresud is the majority owner of the real estate development company IRSA, which is involved in residential properties, office buildings, luxury hotels, shopping centers and financial services (credit cards). Cresud is also growing in the Brazilian agriculture space though its investment in BrasilAgro.
There is a growing demand from emerging market countries for higher quality foods. As these emerging market countries continue to develop, the burgeoning middle class begin to transition from relatively inexpensive staple foods to higher amounts of more expensive animal proteins, as well as fruits and vegetables. More steak, less rice. More hamburgers, less bread. Cresud, as one of Argentina?s largest agriculture companies and a major player in beef cattle raising and animal feed, is a great way to play this increased demand of higher quality foods from the emerging market countries? emerging middle class.
Source: http://avidinvestorgroup.com/2012/08/investing-abroad-argentinian-stocks/
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They didn't stone her to death, as per Islamic law. They must be "moderates."
"Men shave off woman's hair, parade her in streets," from PTI, August 28 (thanks to The Religion of Peace):
Lahore: Five men allegedly shaved off the hair and eyebrows of a young woman and paraded her in the streets of a village in Pakistan's Punjab province, police officials said Tuesday.The incident occurred yesterday in Layyah district, 350 km from Lahore, after the married woman was accused of having "illicit" relations with a man.
According to an FIR registered by police, Parveen Bibi, 25, the wife of Sabir Husain, had a quarrel with her sisters-in-law.
Yesterday, her brothers-in-law Muhammad Pervaiz and Muhammad Zafar and three other men shaved off her hair and eyebrows. They then blackened her face and paraded her through the streets of their village.
Police arrested Parveen's sisters-in-law and a man named Muhammad. The woman?s brothers-in-law are still at large.
Shafiq told police that Parveen had developed "illicit" relations with a man of her neighbourhood.
"We stopped her from meeting him but she continued seeing him," Shafiq, who is related to Parveen, told the police.
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WASHINGTON (AP) ? "2016: Obama's America," a new conservative film exploring the roots of President Barack Obama's political views, took in $6.2 million to make it one of the highest-grossing movies of last weekend. The film, written and narrated by conservative scholar Dinesh D'Souza, argues that Obama was heavily influenced by what D'Souza calls the "anti-colonial" beliefs of his father, Barack Obama Sr., a Kenyan academic who was largely absent from the president's life.
To document that claim, D'Souza travels to Kenya to interview members of Obama's extended family as well as to Hawaii and Indonesia, where Obama grew up. He also cites several actions and policy positions Obama has taken to support the thesis that Obama is ideologically rooted in the Third World and harbors contempt for the country that elected him its first black president.
The assertion that Obama's presidency is an expression of his father's political beliefs, which D'Souza first made in 2010 in his book "The Roots of Obama's Rage," is almost entirely subjective and a logical stretch at best.
It's true that Obama's father lived most of his life in Kenya, an African nation once colonized by the British, and that Obama's reverence for his absent father frames his best-selling memoir. D'Souza even sees clues in the book's title: "Notice it says 'Dreams From My Father,' not 'of' my father," D'Souza says.
But it's difficult to see how Obama's political leanings could have been so directly shaped by his father, as D'Souza claims. The elder Obama left his wife and young son, the future president, when Obama was 2 and visited his son only once, when Obama was 10. But D'Souza frames that loss as an event that reinforced rather than weakened the president's ties to his father, who died in a car crash when Obama was in college.
D'Souza interviews Paul Vitz, a New York University psychologist who has studied the impact of absent fathers on children. In Obama's case, Vitz says, the abandonment meant "he has the tension between the Americanism and his Africanism. He himself is an intersection of major political forces in his own psychology."
From there, the evidence D'Souza uses to support his assertion starts to grow thin.
D'Souza says Obama's mother, Stanley Ann Dunham, shared his father's left-leaning views. After living in Indonesia for several years, D'Souza said, Dunham sent the younger Obama to live with his grandparents in Hawaii so he would not be influenced by her second husband, Lolo Soetoro, an Indonesian who worked for American oil companies and fought communists as a member of the Indonesian army.
"Ann separates Barry from Lolo's growing pro-Western influence," D'Souza says in the film. Obama has said his mother had sent him back to Hawaii so he would be educated in the United States.
In Hawaii, D'Souza asserts with no evidence, Obama sympathized with native Hawaiians who felt they had been marginalized by the American government when Hawaii was becoming a state. D'Souza also asserts ? again with no evidence ? that Obama had been coached to hold those views at Punahou, the prestigious prep school he attended in Honolulu.
"Oppression studies, if you will. Obama got plenty of that when he was here in Punahou," D'Souza says, standing on the campus.
In Kenya, D'Souza interviews Philip Ochieng, a lifelong friend of the president's father, who claims the elder Obama was "totally anti-colonial." Ochieng also discloses some of his own political views, complaining about U.S. policy in Afghanistan and Iraq and saying the U.S. refuses to "tame" Israel, which he calls a "Trojan horse in the Middle East." D'Souza seems to suggest that if a onetime friend of Obama's late father holds those opinions, so too must the president himself.
D'Souza then goes through a list of actions Obama has taken as president to support his thesis. Many of them don't hold water:
? D'Souza rightly argues that the national debt has risen to $16 trillion under Obama. But he never mentions the explosion of debt that occurred under Obama's predecessor, Republican George W. Bush, nor the 2008 global financial crisis that provoked a shock to the U.S. economy.
? D'Souza says Obama is "weirdly sympathetic to Muslim jihadists" in Afghanistan and Pakistan. He does not mention that Obama ordered the raid that killed Osama bin Laden and the drone strikes that have killed dozens of terrorists in the region.
?D'Souza wrongly claims that Obama wants to return control of the Falkland Islands from Britain to Argentina. The U.S. refused in April to endorse a final declaration on Argentina's claim to the islands at the Summit of the Americas, provoking criticism from other Latin American nations.
?D'Souza says Obama has "done nothing" to impede Iran's nuclear ambitions, despite the severe trade and economic sanctions his administration has imposed on Iran to halt its suspected nuclear program. Obama opposes a near-term military strike on Iran, either by the U.S. or Israel, although he says the U.S. will never tolerate a nuclear-armed Iran.
? D'Souza says Obama removed a bust of British Prime Minister Winston Churchill from the Oval Office because Churchill represented British colonialism. White House curator William Allman said the bust, which had been on loan, was already scheduled to be returned before Obama took office. Another bust of Churchill is on display in the president's private residence, the White House says.
___
Follow Beth Fouhy on Twitter at www.twitter.com/bfouhy
EDITOR'S NOTE _ An occasional look at campaign arguments and how well they adhere to the facts.
Source: http://news.yahoo.com/fact-check-anti-obama-film-muddy-facts-072153385--politics.html
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Feature
1UP COVER STORY
1UP COVER STORY | WEEK OF AUGUST 27 | COMMUNITY IN GAMES
T
he elementary school playground is a place where children gather during recess to partake in the unending bliss of childhood exuberance. Four-square is played, tetherballs are knocked back and forth, hundreds of different variations of tag unfold, and the day?s video game rumors are laid out to be discussed. The children often gather at one spot in the playground, one that was perhaps not planned as a spot of meeting, but became one through the spontaneous order that arises from the chaos of school-aged children. Like a gathering of rabbis discussing the intricacies of the Torah, the kids will present to the group rumors and facts about the world of video gaming. Once the statements have been offered, murmurs of approval or disapproval will begin to bubble up from the brief silence. Or perhaps the somewhat level background noise of the playground will be pierced by the disbelieving ?NUH UH!? of a heretic who refuses to believe that there?s a world in Super Mario Bros. called Sky World, and in it Mario flies on a mushroom rocket.
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Source: http://www.chrisjonesgaming.net/gaming-communities-at-the-playground/
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As we welcome Lil' Lorenzo to the world, we offer him some time-tested advice to help guide him through his formative years.
By James Montgomery
Snooki
Photo: D. Dipasupil/ Getty Images
Source: http://www.mtv.com/news/articles/1692598/snooki-baby-lorenzo-advice.jhtml
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Shawsu Workout Studio, 985 Fremont Ave, Los Altos, CA | Get?Directions??
FREE
Meet Los Altos City Council candidate Anabel Pelham.
Join us at Shawsu Fitness Studio to meet Anabel.
"A university professor and Ph.D. social scientist specializing in Gerontology, I was a university administrator for 25 years and managed budgets, staff, faculty, curriculum, and successfully navigated the programs, staff and students through the growing pains and challenges that every university experiences in higher education."
For more information about Anabel please go to www.anabelpelham.org.
37.353014
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August 28, 2012, 6:00 pm?8:00 pm
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985 Fremont Ave, Los Altos, CA
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Source: http://losaltos.patch.com/events/meet-anabel-pelham
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Remember:? If you are participating in the Big Book Summer Challenge, this is the last week!? The challenge officially ends on Monday, Labor Day, so finish your big books and be sure to add your big book review links to the list on the challenge page.
What are you and your family reading this week?
(What are you reading Monday is hosted by Sheila at Book Journey, with a kids/teen version hosted by Teach Mentor Texts.)
My favorite ad for this time of year which has been in my head all morning:
Source: http://greatbooksforkidsandteens.blogspot.com/2012/08/its-monday-827-what-are-you-reading.html
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The downside to cannabis use has been made clearer. The most detailed study yet of the drug's long-term effects shows that those who start a weed habit as teens enter middle age with an 8-point deficit in IQ compared to non-users.
Evidence is growing that cannabis-based drugs can benefit health, but suspicions remain that persistent cannabis use from an early age can have a detrimental effect on cognition. Confirming those suspicions is tricky, though, since cognitive impairment observed later in life could have been present before the drug was first used.
To get around the problem Madeline Meier at Duke University in Durham, North Carolina, and her colleagues have taken the long view. They used a detailed health study which followed 1000 people in Dunedin, New Zealand, from birth until age 38. The data allowed them to compare IQ tests taken by the participants at age 13 ? before any of them began using cannabis ? with the same participants' IQ scores as adults, in some cases after years of cannabis use.
The study showed that those who developed the most persistent dependence on the drug showed the greatest subsequent decline in IQ, losing 6 points on average regardless of how early the habit began. Within that group, those who began taking the drug before their 18th birthday saw a subsequent decline in IQ of 8 points, on average.
Furthermore, friends and relatives close to the persistent cannabis users reported that these users had more everyday memory and attention problems, including forgetting to pay bills and misplacing common items like keys and wallets.
The bad news is that the damage does not appear to be reversed after dropping the habit. But the good news is that people who picked up their drug habit after their 18th birthday did not suffer such severe cognitive decline. Although previous research has hinted at the potential impacts of cannabis on the adolescent brain, this study is the first to provide evidence that cannabis does in fact have neurotoxic effects on young brains, says Meier.
Journal reference: Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.1206820109
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Beats By Dre Beats By Dre The best way to do Advertising for the House Business
Dwelling companies, like other businesses, are not prosperous simply because they exist. If you want to perform at residence, you need to discover about advertising and marketing a dwelling based business.
Advertising and marketing depends in large part on the type of small business you have. Promoting on the web functions for most sorts of property organization. Even if you program the bulk of one?s enterprise from your nearby region, a site adds professionalism. When sending emails, be sure you include things like facts about your business in your signature file.
interrupted to complete it, as they may be on the phone. When emailing former clientele, let them know you enjoyed working with them and want them to keep in mind you for future projects.
Look for techniques to meet possible prospects. Visit trade meetings or convOf course, if your residence based business can also be internet-based, it truly is necessary for you personally to study ray ban sunglasses to market on the web. Procedures for advertising a household based enterprise on the net consist of pay-per-click advertising, weblogs, and your web page. You are able to also network on line by means of message boards and mailing lists.
An frequently overlooked tool for marketing and advertising a residence based organization is staying in touch with former clientele. You could do this via the telephone or through e-mail. E-mail is frequently the preferred choice for the reason that possible clients check out e-mail when they have time and are not entions. For instance, if you are selling pet items, attend dog shows and county fairs.
The big ways to for promoting a home based small business are related to other companies. Discover prospects you could serve and locate ways to let them know you exist. Following they grow to be clients, serve them well and ask for future business enterprise. This is how you hold your business operating.
On-line Marketing and advertising Techniques
For those who own a web-site or other business enterprise online, you need shoppers. With all of the competing internet websites, how do they come across you
You?ll want to have some fantastic tactics formarketing and advertising an online enterprise. Certainly one of the most employed strategies for markeing a web based company is studying to acquire a high search engine ranking. In case you don?t rank very you may have difficulty being discovered.
There are some key methods for high ranking. Start out by keeping everything on your web site related for the subject. This makes good sense anyway for the reason that as soon as the consumer has located you, you desire him to stick around. Pick a domain name and site title that fit properly together with your business search phrases. Your title should be simple to bear in mind. Links to your web-site make a distinction in search engine rankings, so speak to web sites that give facts complementing yours and ask for reciprocal links. Be conscious that this details can change as search engines like google redesign their procedures for related results.
Another method for advertising and marketing a web based business is to use pay-per-click advertising. This could be a fast solution to get listed high within the search engines like google. You can find a number of providers of pay-per-click marketing. It pays to verify out a assortment to determine which suits your requires the most effective.
Weblogs are a newer source for advertising an online enterprise. They have a tendency to rank nicely, and buyers like them. Use your blog to talk about your market and deliver links to your internet site. Blogs add a good deal for your promoting program and may be fun to write.
Certainly one of the best methods is to write articles and to submit them to write-up directories. Right here are just some of the positive aspects you?ll get by submitting articles to report directories:
=> Improve the incoming links pointing to your web page ? Search engines like google use links as a gauge for determining how ?important? your site is. Search engines view every link pointing for your web site as a ?vote? along with the much more votes your web site receives, the greater the rankings!
=> Increase your site traffic, sales, and newsletter options ? Any time you submit articles to an article directory, your articles can be picked up by other web-sites, newsletters, and ezines. This may make additional website traffic and lead to a lot more exposure!
=> Gain ?expert? status and turn out to be recognized as an authority within your field ? By publishing superior info packed articles, you are going to soon appreciate the status of becoming observed as an authority on your topic. This can result in joint ventures and lots of other thrilling possibilities which you would have never enjoyed otherwise!
Promoting a web based enterprise is important for success. Use each of the marketing and advertising approaches at your disposal and watch your targeted traffic grow.
Source: http://www.sendyougift.com/activity/p/111711/
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AAJA New York member and food writer Cheryl Tan is coming to Hong Kong in October for the International Literary Festival, Oct. 5-14. Tan is the author of A Tiger in the Kitchen, a memoir about how she discovered her Singaporean family through cooking. (Read her blog here)
Tan will be speaking with Fuchsia Dunlop and chef Tracy Griffiths. Tan?will also be?doing a memoir-writing workshop and a panel on the business of food writing on Sunday, October 7. More details to come on the HKILF blog.
Be the first to like this.
Source: http://aajaasia.wordpress.com/2012/08/27/aaja-food-writer-to-speak-at-hk-literary-festival/
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BERLIN (AP) ? Germany's economy minister has rejected calls for Greece to get more time to implement economic reforms, saying in an interview Sunday that Athens needs to respect the bailout deal reached with its international creditors.
Philipp Roesler's comments to ZDF public television come after a visit by Greece's prime minister to Berlin on Friday, during which Antonis Samaras told German Chancellor Angela Merkel that his country needs "time to breathe" before it can make all the budget cuts and reforms demanded as part of its ?240 billion ($300 billion) bailout packages.
"What the Greeks have asked for, half a year or two years, that's not doable," said Roesler, who is also the vice chancellor in Angela Merkel's coalition government. He added that "time is always money" and all parties had agreed that additional funds for Greece weren't up for debate.
Roesler, the leader of Germany's pro-business Free Democratic Party, has long taken a hard line on Greece. Last month, he caused an outcry in Greece by suggesting the idea of the country leaving the 17-nation eurozone had "lost its horror."
Those comments appeared to put him at odds with Merkel, who has always insisted that Greece should remain in the euro.
But his latest views on the need for Greece to stick to the agreed time plan for reforms were echoed by German Finance Minister Wolfgang Schaeuble, who told a newspaper in comments published Sunday that "more time generally means more money and that quickly means a new (bailout) program."
Merkel has so far shied away from making new promises to Greece. On Sunday, she dodged questions on the subject during an interview with German public TV station ARD. Instead, she insisted that "we are at a crucial moment in the fight against the debt crisis and that's why I think we should all weigh our words carefully."
The question of how to avert a Greek debt default, which could spark a chain reaction among other ailing European economies, has preoccupied EU leaders as they return from their traditional summer break.
French President Francois Hollande urged Greece on Saturday to do more to show its commitment to reforms, and offered the country no immediate hope for relief from its current regime of painful austerity measures. Like Merkel, Hollande said further decisions on Greece need to wait for a report next month by the country's debt inspectors.
Meanwhile, the respected German weekly Der Spiegel reported in its latest edition that Merkel wants EU leaders to forge ahead with deeper political integration within the unwieldy 27-nation bloc.
Merkel has long advocated closer political integration as a means of preventing the European project from unraveling under the strain caused by the eurozone crisis.
Asked about her plans, the chancellor told ARD television Sunday: "Our task now is to remove the founding mistakes of the currency union, namely the lack of political cooperation, and that's what we are going to discuss in the coming months."
She suggested that EU member state could be subject to closer budget scrutiny, and that measures such as tax harmonization could be up for discussion.
Source: http://news.yahoo.com/german-minister-rejects-more-time-greece-125306678.html
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Source: http://www.flattier.com/2012/08/ontario-place-facelift-to-include-new.html
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CINCINNATI (AP) ? Neil Armstrong was a soft-spoken engineer who became a global hero when as a steely-nerved pilot he made "one giant leap for mankind" with a small step onto the moon. The modest man, who had people on Earth entranced and awed from almost a quarter-million miles away, but credited others for the feat, died Saturday. He was 82.
Armstrong died following complications resulting from cardiovascular procedures, his family said in a statement. Armstrong had had a bypass operation this month, according to NASA. His family didn't say where he died; he had lived in suburban Cincinnati.
Armstrong commanded the Apollo 11 spacecraft that landed on the moon July 20, 1969, capping the most daring of the 20th century's scientific expeditions. His first words after becoming the first person to set foot on the surface are etched in history books and the memories of those who heard them in a live broadcast.
"That's one small step for man, one giant leap for mankind," Armstrong said.
(Armstrong insisted later that he had said "a'' before man, but said he, too, couldn't hear it in the version that went to the world.)
In those first few moments on the moon, during the climax of a heated space race with the Soviet Union, Armstrong stopped in what he called "a tender moment" and left a patch to commemorate NASA astronauts and Soviet cosmonauts who had died in action.
"It was special and memorable but it was only instantaneous because there was work to do," Armstrong told an Australian television interviewer this year.
Armstrong and Buzz Aldrin spent nearly three hours walking on the lunar surface, collecting samples, conducting experiments and taking photographs.
"The sights were simply magnificent, beyond any visual experience that I had ever been exposed to," Armstrong once said.
The moonwalk marked America's victory in the Cold War space race that began Oct. 4, 1957, with the launch of the Soviet Union's Sputnik 1, a 184-pound satellite that sent shock waves around the world.
Although he had been a Navy fighter pilot, a test pilot for NASA's forerunner and an astronaut, Armstrong never allowed himself to be caught up in the celebrity and glamour of the space program.
"I am, and ever will be, a white socks, pocket protector, nerdy engineer," he said in 2000 in one of his rare public appearances. "And I take a substantial amount of pride in the accomplishments of my profession."
Rice University historian Douglas Brinkley, who interviewed Armstrong for oral histories for NASA, said Armstrong fit every requirement the space agency needed for the first man to walk on moon, especially because of his engineering skills and the way he handled celebrity by shunning it.
?????????"I think his genius was in his reclusiveness," said Brinkley. "He was the ultimate hero in an era of corruptible men."
Fellow Ohioan and astronaut John Glenn, one of Armstrong's closest friends, recalled Saturday how Armstrong was down to the last 15 seconds to 35 seconds of fuel when he finally brought the lunar module Eagle down on the Sea of Tranquility.
"That showed a dedication to what he was doing that was admirable," Glenn said.
A man who kept away from cameras, Armstrong went public in 2010 with his concerns about President Barack Obama's space policy that shifted attention away from a return to the moon and emphasized private companies developing spaceships. He testified before Congress, and in an email to The Associated Press, Armstrong said he had "substantial reservations," and along with more than two dozen Apollo-era veterans, he signed a letter calling the plan a "misguided proposal that forces NASA out of human space operations for the foreseeable future."
Armstrong was among the greatest of American heroes, Obama said in a statement.
"When he and his fellow crew members lifted off aboard Apollo 11 in 1969, they carried with them the aspirations of an entire nation. They set out to show the world that the American spirit can see beyond what seems unimaginable ? that with enough drive and ingenuity, anything is possible," Obama said.
Obama's Republican opponent Mitt Romney echoed those sentiments, calling Armstrong an American hero whose passion for space, science and discovery will inspire him for the rest of his life.
"With courage unmeasured and unbounded love for his country, he walked where man had never walked before. The moon will miss its first son of earth," Romney said.
NASA Administrator Charles Bolden recalled Armstrong's grace and humility.
"As long as there are history books, Neil Armstrong will be included in them, remembered for taking humankind's first small step on a world beyond our own," Bolden said in a statement.
Armstrong's modesty and self-effacing manner never faded.
When he appeared in Dayton in 2003 to help celebrate the 100th anniversary of powered flight, he bounded onto a stage before 10,000 people packed into a baseball stadium. But he spoke for only a few seconds, did not mention the moon, and quickly ducked out of the spotlight.
He later joined Glenn, by then a senator, to lay wreaths on the graves of Wilbur and Orville Wright. Glenn introduced Armstrong and noted it was 34 years to the day that Armstrong had walked on the moon.
"Thank you, John. Thirty-four years?" Armstrong quipped, as if he hadn't given it a thought.
At another joint appearance, the two embraced and Glenn commented: "To this day, he's the one person on earth I'm truly, truly envious of."
Armstrong's moonwalk capped a series of accomplishments that included piloting the X-15 rocket plane and making the first space docking during the Gemini 8 mission, which included a successful emergency splashdown.
In the years afterward, Armstrong retreated to the quiet of the classroom and his southwestern Ohio farm. Aldrin said in his book "Men from Earth" that Armstrong was one of the quietest, most private men he had ever met.
In the Australian interview, Armstrong acknowledged that "now and then I miss the excitement about being in the cockpit of an airplane and doing new things."
At the time of the flight's 40th anniversary, Armstrong again was low-key, telling a gathering that the space race was "the ultimate peaceful competition: USA versus U.S.S.R. It did allow both sides to take the high road with the objectives of science and learning and exploration."
Glenn, who went through jungle training in Panama with Armstrong as part of the astronaut program, described him as "exceptionally brilliant" with technical matters but "rather retiring, doesn't like to be thrust into the limelight much."
Derek Elliott, curator of the Smithsonian Institution's U.S. Air and Space Museum from 1982 to 1992, said the moonwalk probably marked the high point of space exploration.
The manned lunar landing was a boon to the prestige of the United States, which had been locked in a space race with the former Soviet Union, and re-established U.S. pre-eminence in science and technology, Elliott said.
"The fact that we were able to see it and be a part of it means that we are in our own way witnesses to history," he said.
The 1969 landing met an audacious deadline that President John F. Kennedy had set in May 1961, shortly after Alan Shepard became the first American in space with a 15-minute suborbital flight. (Soviet cosmonaut Yuri A. Gagarin had orbited the Earth and beaten the U.S. into space the previous month.)
"I believe this nation should commit itself to achieving the goal, before the decade is out, of landing a man on the moon and returning him safely to Earth," Kennedy had said. "No single space project in this period will be more impressive to mankind, or more important to the long-range exploration of space; and none will be so difficult or expensive to accomplish."
The end-of-decade goal was met with more than five months to spare. "Houston: Tranquility Base here," Armstrong radioed after the spacecraft settled onto the moon. "The Eagle has landed."
"Roger, Tranquility," Apollo astronaut Charles Duke radioed back from Mission Control. "We copy you on the ground. You've got a bunch of guys about to turn blue. We're breathing again. Thanks a lot."
The third astronaut on the mission, Michael Collins, circled the moon in the mother ship Columbia 60 miles overhead while Armstrong and Aldrin went to the moon's surface.
"He was the best, and I will miss him terribly," Collins said through NASA.
In all, 12 American astronauts walked on the moon from 1969 to the last moon mission in 1972.
For Americans, reaching the moon provided uplift and respite from the Vietnam War, from strife in the Middle East, from the startling news just a few days earlier that a young woman had drowned in a car driven off a wooden bridge on Chappaquiddick Island by Sen. Edward Kennedy. The landing occurred as organizers were gearing up for Woodstock, the legendary three-day rock festival on a farm in the Catskills of New York.
Armstrong was born Aug. 5, 1930, on a farm near Wapakoneta in western Ohio. He took his first airplane ride at age 6 and developed a fascination with aviation that prompted him to build model airplanes and conduct experiments in a homemade wind tunnel.
As a boy, he worked at a pharmacy and took flying lessons. He was licensed to fly at 16, before he got his driver's license.
Armstrong enrolled in Purdue University to study aeronautical engineering but was called to duty with the U.S. Navy in 1949 and flew 78 combat missions in Korea.
After the war, Armstrong finished his degree from Purdue and later earned a master's degree in aerospace engineering from the University of Southern California. He became a test pilot with what evolved into the National Aeronautics and Space Administration, flying more than 200 kinds of aircraft from gliders to jets.
Armstrong was accepted into NASA's second astronaut class in 1962 ? the first, including Glenn, was chosen in 1959 ? and commanded the Gemini 8 mission in 1966. After the first space docking, he brought the capsule back in an emergency landing in the Pacific Ocean when a wildly firing thruster kicked it out of orbit.
Armstrong was backup commander for the historic Apollo 8 mission at Christmastime in 1968. In that flight, Commander Frank Borman, Jim Lovell and Bill Anders circled the moon 10 times, paving the way for the lunar landing seven months later.
Aldrin said he and Armstrong were not prone to free exchanges of sentiment.
"But there was that moment on the moon, a brief moment, in which we sort of looked at each other and slapped each other on the shoulder ... and said, 'We made it. Good show,' or something like that," Aldrin said.
An estimated 600 million people ? a fifth of the world's population ? watched and listened to the landing, the largest audience for any single event in history.
Parents huddled with their children in front of the family television, mesmerized by what they were witnessing. Farmers abandoned their nightly milking duties, and motorists pulled off the highway and checked into motels just to see the moonwalk.
Television-less campers in California ran to their cars to catch the word on the radio. Boy Scouts at a camp in Michigan watched on a generator-powered television supplied by a parent.
Afterward, people walked out of their homes and gazed at the moon, in awe of what they had just seen. Others peeked through telescopes in hopes of spotting the astronauts.
In Wapakoneta, media and souvenir frenzy was swirling around the home of Armstrong's parents.
"You couldn't see the house for the news media," recalled John Zwez, former manager of the Neil Armstrong Air and Space Museum. "People were pulling grass out of their front yard."
Armstrong, Aldrin and Collins were given ticker tape parades in New York, Chicago and Los Angeles and later made a 22-nation world tour. A homecoming in Wapakoneta drew 50,000 people to the city of 9,000.
In 1970, Armstrong was appointed deputy associate administrator for aeronautics at NASA but left the following year to teach aerospace engineering at the University of Cincinnati.
He remained there until 1979 and during that time bought a 310-acre farm near Lebanon, where he raised cattle and corn. He stayed out of public view, accepting few requests for interviews or speeches.
"He didn't give interviews, but he wasn't a strange person or hard to talk to," said Ron Huston, a colleague at the University of Cincinnati. "He just didn't like being a novelty."
Those who knew him said he enjoyed golfing with friends, was active in the local YMCA and frequently ate lunch at the same restaurant in Lebanon.
In 2000, when he agreed to announce the top 20 engineering achievements of the 20th century as voted by the National Academy of Engineering, Armstrong said there was one disappointment relating to his moonwalk.
"I can honestly say ? and it's a big surprise to me ? that I have never had a dream about being on the moon," he said.
From 1982 to 1992, Armstrong was chairman of Charlottesville, Va.-based Computing Technologies for Aviation Inc., a company that supplies computer information management systems for business aircraft.
He then became chairman of AIL Systems Inc., an electronic systems company in Deer Park, N.Y.
Armstrong married Carol Knight in 1999, and the couple lived in Indian Hill, a Cincinnati suburb. He had two adult sons from a previous marriage.
Armstrong's is the second death in a month of one of NASA's most visible, history-making astronauts. Sally Ride, the first American woman in space, died of pancreatic cancer on July 23 at age 61.
Just prior to the 50th anniversary of Glenn's orbital flight this past February, Armstrong offered high praise to the elder astronaut and said that Glenn had told him many times how he wished he, too, had flown to the moon on Apollo 11. Glenn said it was his only regret.
Noted Armstrong in an email: "I am hoping I will be 'in his shoes' and have as much success in longevity as he has demonstrated." Glenn is 91.
At the Griffith Observatory in Los Angeles on Saturday, visitors held a minute of silence for Armstrong.
For anyone else who wanted to remember him, his family's statement made a simple request:
"Honor his example of service, accomplishment and modesty, and the next time you walk outside on a clear night and see the moon smiling down at you, think of Neil Armstrong and give him a wink."
___
Borenstein reported from Washington. Associated Press writer Steve Peoples in New Hampshire and AP Science Writers Alicia Chang in Los Angeles and Marcia Dunn in Cape Canaveral, Fla., contributed to this report.
Source: http://news.yahoo.com/neil-armstrong-1st-man-moon-dies-82-200215442--finance.html
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Friday, August 24, 2012 10:28 PM EDT
James DrzewieckiBuster Bash is an app available on apple devices and if you want a game that is similar to Angry Birds but with a baseball theme, well this would be it.
Now, let me say this ? this isn?t a perfect app. I did run into two issues that did make me like it less, but I?ll get into that later.
First, here is an overview of the game. You play as, well, your finger as you follow a boy named Buster in his baseball career. You start in his backyard in Leesburg, Georgia and as you progress you end up in the Big Leagues.
In each round you get 10 baseballs and the goal is to hit as many home runs as you can. As you hit balls you will earn sunflower seeds and these can be used to buy power-ups and equipment to help you hit those balls even farther.The way you hit these balls is by swiping your finger across the screen, where my first annoyances with the game.
It could be just me but sometimes when I swipe my finger across the screen and clearly connect with a ball, the ball just goes right through my hit. It?s annoying and I could be wrong, I could be missing them, but I?m 97 percent sure I?m not.
The other is all the game?s fault. There comes a point in the game when the pitcher throws the ball and the ball bounces off the back of his head and falls. This will cause you to get 0 Feet. I can see if it happened once, but this happened at least seven times in a row.
Yet, when the game works it works great and it?s free to download and play. It?s not as smooth or fun as ?Angry Birds? but it takes a lot of hints from that game and tries to deliver something new and refreshing and for the most part it works.
One thing that I dislike about all these apps, not just Buster Bash, is paying real money to achieve in-game currency. I brought this up awhile ago in a column where I talked bout the new Tiger Woods game. In these games you can just dish out real money to unlock currency, in this case sunflower seeds, to buy new equipment. Yes, you can collect sunflower seeds in the game and choose not to buy it for real but why even give us the option? I hate this option because if you?re feeling lazy you will just buy the in-game currency and it cheapens the experience. I know some people like this option, but come on you have to admit that it does take away most of the challenge, because if you get in a tight spot you?re not going to worry because you can just buy your way out.
These options to buy-in game currency should be taken out. If the companies want to make money off these apps then charge for the app and later release level packs you can also charge us for.
Closing out this week I want to say that app?s are becoming more and more popular and there is some great ones out there. But I will say that mobile phones app can?t compete fully with Nintendo or Sony?s handhelds. Yet, I do believe that it?s headed that way.
In the future I would like to see phones being able to bring full handheld versions of sports games that are also available on Nintendo?s and Sony?s systems. But until then the smart phones are giving us a different type of gaming and that?s fine, it separates it from the others.
James Drzewiecki can be reached
at (860) 584-0501 ext. 22 or
jdrzewiecki@bristolpress.com
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Source: http://www.newbritainherald.com/articles/2012/08/24/sports/doc503837100d8bd965239006.txt
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FILE - This file combination photo made from file images provided by the U.S. Food and Drug Administration shows two of nine cigarette warning labels from the FDA. A federal appeals court on Friday, Aug. 24, 2012, upheld a decision barring the federal government from requiring tobacco companies to put large graphic health warnings on cigarette packages to show that smoking can disfigure and even kill people. (AP Photo/U.S. Food and Drug Administration, File)
FILE - This file combination photo made from file images provided by the U.S. Food and Drug Administration shows two of nine cigarette warning labels from the FDA. A federal appeals court on Friday, Aug. 24, 2012, upheld a decision barring the federal government from requiring tobacco companies to put large graphic health warnings on cigarette packages to show that smoking can disfigure and even kill people. (AP Photo/U.S. Food and Drug Administration, File)
RICHMOND, Va. (AP) ? The federal government can't require tobacco companies to put large graphic health warnings on cigarette packages to show that smoking can disfigure and even kill people, a divided federal appeals court panel ruled Friday.
In a 2-1 decision, the U.S. Court of Appeals in Washington affirmed a lower court ruling that the requirement ran afoul of the First Amendment's free speech protections. The appeals court tossed out the requirement and told the Food and Drug Administration to go back to the drawing board. The decision is considered a blow to one of the Obama administration's major public health initiatives, raises the prospect of another U.S. Supreme Court tobacco battle and opens the door to further challenges of FDA's regulatory scheme.
Some of the nation's largest tobacco companies, including R.J. Reynolds Tobacco Co., sued to block the mandate to include warnings to show the dangers of smoking and encouraging smokers to quit lighting up. They argued that the proposed warnings went beyond factual information into anti-smoking advocacy. The government argued the photos of dead and diseased smokers are factual in conveying the dangers of tobacco, which is responsible for about 443,000 deaths in the U.S. a year.
The nine graphic warnings proposed by the FDA include color images of a man exhaling cigarette smoke through a tracheotomy hole in his throat, and a plume of cigarette smoke enveloping an infant receiving a mother's kiss. These are accompanied by language that says smoking causes cancer and can harm fetuses. The warnings were to cover the entire top half of cigarette packs, front and back, and include the phone number for a stop-smoking hotline, 1-800-QUIT-NOW.
In the majority opinion, the appeals court wrote that the case raises "novel questions about the scope of the government's authority to force the manufacturer of a product to go beyond making purely factual and accurate commercial disclosures and undermine its own economic interest ? in this case, by making 'every single pack of cigarettes in the country (a) mini billboard' for the government's anti-smoking message."
The court also wrote that the FDA "has not provided a shred of evidence" showing that the warnings will "directly advance" its interest in reducing the number of Americans who smoke.
Tobacco companies increasingly rely on their packaging to build brand loyalty and grab consumers ? one of the few advertising levers left to them after the government curbed their presence in magazines, billboards and TV.
"It's a significant vindication of First Amendment principles," said Floyd Abrams, an attorney representing Lorillard Tobacco. "There's never been any doubt that the government could require warnings on products that can have dangerous results. And what the court is saying is that there are real limits on the ability of the government to require the manufacturer of a lawful product to denounce the product in the course of trying to sell it."
The FDA declined to comment on pending litigation and the Justice Department said it would review the appeals court ruling.
In a statement, the Department of Health and Human Services said the administration is "determined to do everything we can" to warn people about the dangers of smoking, and that the labels are an "effective tool" in those efforts.
Public health groups are urging the government to appeal.
"While the tobacco industry has grown increasingly aggressive in preying upon the American public with misleading and fraudulent marketing practices over several decades, the warning labels have not been changed in 25 years," John R. Seffrin, chief executive of the American Cancer Society, said in a statement. "Existing warnings have failed to inform the public adequately of the risks of tobacco use. ... We hope the government can identify ways that the FDA can move forward with the new cigarette warning labels."
Warning labels first appeared on U.S. cigarette packs in 1965, and current warning labels that feature a small box with text were put on cigarette packs in the mid-1980s. Changes to more graphic warning labels that feature color images of the negative effects of tobacco use were mandated in a law passed in 2009 that, for the first time, gave the federal government authority to regulate tobacco.
The share of Americans who smoke has fallen dramatically since 1970, from nearly 40 percent to about 20 percent. But the rate has stalled since about 2004, with about 46 million adults in the U.S. smoking cigarettes. It's unclear why it hasn't budged, but some experts have cited tobacco company discount coupons on cigarettes and lack of funding for programs to discourage smoking or to help smokers quit.
In recent years, more than 40 countries or jurisdictions have introduced labels similar to those created by the FDA. The World Health Organization said in a survey done in countries with graphic labels that a majority of smokers noticed the warnings and more than 25 percent said the warnings led them to consider quitting.
Joining North Carolina-based R.J. Reynolds, owned by Reynolds American Inc., and Lorillard Tobacco, owned by Lorillard Inc., in the lawsuit are Commonwealth Brands Inc., Liggett Group LLC and Santa Fe Natural Tobacco Company Inc.
Richmond, Va.-based Altria Group Inc., parent company of the nation's largest cigarette maker, Philip Morris USA, which makes the top-selling Marlboro brand, is not a part of the lawsuit.
The case is separate from a lawsuit by several of the same tobacco companies over the 2009 Family Smoking Prevention and Tobacco Control Act, which cleared the way for the more graphic warning labels and other marketing restrictions. The law also allowed the FDA to limit nicotine and banned tobacco companies from sponsoring athletic or social events or giving away free samples or branded merchandise.
In March, a federal appeals court in Cincinnati ruled that the law was constitutional. The contradicting decisions mean the case could be settled by the U.S. Supreme Court on appeal.
___
Michael Felberbaum can be reached at http://www.twitter.com/MLFelberbaum
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King Richard III of England had the honor of being memorialized in a William Shakespeare play after his death in battle in 1485. Now, modern-day archaeologists are on the hunt for the medieval king's physical resting place.
The University of Leicester, Leicester City Council and the Richard III Society have joined forces to search for the grave of Richard III, thought to be under a parking lot for city council offices. The team will use ground-penetrating radar to search for the ideal spots to dig.
"This archaeological work offers a golden opportunity to learn more about medieval Leicester as well as about Richard III's last resting place ? and, if he is found, to re-inter his remains with proper solemnity in Leicester Cathedral," Philippa Langley, a Richard III Society member, said in a statement.
Richard III was King of England from 1483 to 1485. He died during the Battle of Bosworth Field during the War of the Roses, an English civil war between the House of Lancaster and the House of York. Richard III was the last English king to die in battle. Shakespeare penned "Richard III," a play about the tragic king, approximately 100 years later.
Regardless of his Shakespeare claim to fame, the king was talked about for his own right. "Richard III is a charismatic figure who attracts tremendous interest, partly because he has been so much maligned in past centuries, and partly because he occupies a pivotal place in English history," Langley said.
"The continuing interest in Richard means that many fables have grown up around his grave." Langley said, ?adding that some far-fetched tales include that the bones were thrown into the river Soar. [The Science of Death: 10 Tales from the Crypt]
"Other fables, equally discredited, claimed that his coffin was used as a horse-trough," Langley said.
After his death, the king was stripped and brought to Leicester, where he was buried in the church of the Franciscan Friary, known as the Greyfriars. The location of Greyfriars was eventually lost to history.?
"The big question for us is determining the whereabouts of the church on the site and also where in the church the body was buried," University of Leicester archaeologist Richard Buckley said in a statement. "Although in many ways finding the remains of the king is a long-shot, it is a challenge we shall undertake enthusiastically. There is certainly potential for the discovery of burials within the area, based on previous discoveries and the postulated position of the church."
The search begins on Aug. 25. If remains that could be Richard III are found, they will be subject to DNA analysis at the University of Leicester.
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Copyright 2012 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.Source: http://news.yahoo.com/grave-king-richard-iii-may-hidden-under-parking-230321702.html
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There are various categories of sports supplements. Some of them are made with the intention of helping with fat burning and weight loss. The easiest way of burning fat is of course by eating less and by doing exercises, but there are certain supplements that can help burn the fat much faster.
If you choose one of the ?fat burners?, make sure you stick to the ones that do not have dangerous stimulants such as Ephedra. ?Thermogenic? supplements are said to enhance your metabolism so as to burn the fat at a faster pace by increasing your body?temperature. ?Our advice, stay away! ?The problem with thermogenics?is they have a?myriad?of side effects that can have both short and long term health consequences including ?irregular heartbeat, insomnia, and elevated blood pressure.?The other disappointing reality is the moment you stop taking them you will likely regain all the weight you lost. ?This is not a sustainable or healthy solution.
Healthier Alternatives
Fish oils have attracted plenty of attention as sports supplements in recent years and with good reason. They have become popular fatty acids taken by a growing number of people for cholesterol control or heart health benefits.
The Omega 6 and Omega 3 fats can be combined with appropriate exercise to achieve the best fat loss results. ?Pumpkin seed oils, coconut oils and flaxseed oils are also beneficial in improving performance on the field. Not only do they enhance athletic performance, but also improve the health of your heart.
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