Monday, July 15, 2013

New wonder drug matches and kills all kinds of cancer

Stanford researchers are on track to begin human trials of a potentially potent new weapon against cancer, and would-be participants are flooding in following the Post?s initial report on the discovery.?The progress comes just two months after the ground-breaking study by Dr Irv Weissman, who developed an antibody that breaks down a cancer?s defense mechanisms in the body.

A protein called CD47 tells the body not to ?eat? the cancer, but the antibody developed by Dr Weissman blocks CD47 and frees up immune cells called macrophages ? which can then engulf the deadly cells.

The new research shows the miraculous macrophages effectively act as intelligence gatherers for the body, pointing out cancerous cells to cancer-fighting ?killer T? cells.?The T cells then ?learn? to hunt down and attack the cancer, the researchers claim.

?It was completely unexpected that CD8+ T (killer T) cells would be mobilized when macrophages engulfed the cancer cells in the presence of CD47-blocking antibodies,? said MD/PhD student Diane Tseng, who works with Dr. Weissman.

The clinical implications of the process could be profound in the war on cancer.?When macrophages present ?killer T? cells with a patient?s cancer, the T cells become attuned to the unique molecular markers on the cancer.?This turns them into a personalized cancer vaccine.

?Because T cells are sensitized to attack a patient?s particular cancer, the administration of CD47-blocking antibodies in a sense could act as a personalized vaccination against that cancer,? Tseng said.

The team of researchers at Stanford plan on starting a small 10-100 person phase I clinical human trial of the cancer therapy in 2014. Via New wonder drug matches and kills all kinds of cancer

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Source: http://deskarati.com/2013/07/14/new-wonder-drug-matches-and-kills-all-kinds-of-cancer/?utm_source=rss&utm_medium=rss&utm_campaign=new-wonder-drug-matches-and-kills-all-kinds-of-cancer

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Yahoo accepting requests for inactive email IDs

(AP) ? Yahoo is allowing people to place claims on inactive email addresses that are being given a second life.

The opportunity to request the identifications began Monday and will extend through Aug. 7. Up to five different names can be submitted at http://wishlist.yahoo.com .

Yahoo Inc. says a substantial number of old email IDs are being made available, but isn't providing specifics. All the deactivated accounts haven't been used in at least a year.

The dormant email IDs are being released a month after the Sunnyvale, Calif., company notified users that they would have 30 days to log into an inactive account if they wanted to keep it.

People awarded the rights to the recycled email addresses will have a 48-hour period to activate the accounts beginning Aug. 15.

Yahoo is hoping the inactive IDs will be claimed by people who will use them to log into its website and discover a series of changes to its email, home page and other services that have been made since Marissa Mayer became the company's CEO a year ago.

The resurrection of inactive email addresses, however, could be exploited by computer hackers hoping to use the IDs to pry into sensitive information about the former accountholders. There's a risk because many people use their email accounts as logins at a different password-protected websites, including Facebook, Twitter and Amazon.com. That raises the specter of some people trying to use the recycled email IDs to request the passwords of former accountholders.

Yahoo says it has taken a series of security measures to minimize the chances of any mischief. Among other things, Yahoo says emails are now being bounced back from the inactive email accounts. The company says it has also developed a system that will help other websites identify email addresses that have been transferred to new accountholders after the recycling is completed.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-07-15-US-Yahoo-IDs/id-c49c1b2c665a49eeb3b86e10055766b4

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Friday, July 12, 2013

Purported Verizon roadmap: Moto X launches August 23rd, HTC One on August 1st

Verizon HTC One, Moto X Release DateVerizon HTC One, Moto X Release Date

Verizon has been awfully quiet about exactly?when it plans to release the HTC One on its network, but a purported Verizon product roadmap obtained by PhoneArena suggests that both the HTC One and the upcoming Motorola Moto X could both launch by the start of September. Specifically, the document supposedly shows that the HTC One will launch on August 1st while the Moto X will be released on August 23rd, which means both devices would be available in time for back-to-school shoppers. Earlier rumors indicated that Verizon wouldn?t have the HTC One on its network until September 5th so it?s a pleasant surprise to hear that the carrier might be supporting the device a little bit sooner.

[More from BGR: High-quality photos of iPhone 5S display leak for the first time]

This article was originally published on BGR.com

Source: http://news.yahoo.com/purported-verizon-roadmap-moto-x-launches-august-23rd-191021197.html

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AMERICAN CANCER Society Cancer/Caregiver Support Group Meeting

AMERICAN CANCER Society Cancer/Caregiver Support Group Meeting


When: July 16, 2013
06:00 PM to 08:00 PM

Description: AMERICAN CANCER Society Cancer/Caregiver Support Group Meeting will be held July 16 at 6 p.m. in the conference room of Comfort Inn, Highway 67.

Source: http://community.statesboroherald.com/events/detail/25220/

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FDA sets new limits on arsenic in apple juice

WASHINGTON (AP) ? Parents who have been fretting over the low levels of arsenic found in apple juice can feel better about buying one of their kids' favorite drinks.

The Food and Drug Administration is setting a new limit on the level of arsenic allowed in apple juice, after more than a year of public pressure from consumer groups worried about the contaminant's effects on children. Nationwide, apple juice is second only to orange juice in popularity, according to industry groups.

Studies have shown that the juice contains very low levels of arsenic, a cancer-causing agent found in everything from water to soil to pesticides. The FDA has monitored arsenic in apple juice for decades and has long said the levels are not dangerous to consumers, in particular small children who favor fruit juice.

But now the agency is putting in place a strict standard on how much arsenic is acceptable in apple juice, limiting the amount to the same level currently permitted in drinking water.

Under the new regulation, apple juice containing more than 10 parts per billion could be removed from the market and companies could face legal action. Agency officials stressed that the vast majority of juices on the market are already below the threshold.

"Overall the supply of apple juice is very safe and does not represent a threat to public health," said FDA Commissioner Dr. Margaret Hamburg, in an interview with The Associated Press. "We decided to put forward this proposed action level to give guidance to industry and to assure ongoing safety and quality."

An FDA analysis of dozens of apple juice samples last year found that 95 percent were below the new level.

The standard specifically targets inorganic arsenic ? the type found in pesticides ? which can be toxic and may pose a cancer risk if consumed at high levels or over a long period. Organic arsenic occurs naturally in dirt and soil and passes through the body quickly without causing harm, according to the FDA.

In 2008 FDA regulators set a "level of concern" for arsenic at 23 parts per billion in apple juice. The agency has the authority to seize juice that exceeds that level.

But agency officials played down the significance of the older figure this week, calling it a "back of the envelope" calculation that was used to assess one juice shipment detained at the border.

"It was not a full blown, science-based number," said Michael Taylor, FDA's deputy commissioner for foods.

The FDA's new number is based on lifetime exposure to arsenic and the potential for long-term cancer risk. Taylor says the number reflects a very cautious approach, since it's unclear how much arsenic exposure can trigger the disease.

"There isn't a known threshold for the carcinogenic effect, so we assume the possibility of effects all the way down to the lowest dose," Taylor said.

The agency will take comments on the draft regulation for 60 days before making it binding.

Consumers Union, publisher of Consumer Reports, last year called for a limit as low as 3 parts per billion. While the FDA didn't go that far, the group still praised the agency for taking action.

"While we had proposed a lower limit, we think this is a perfectly good first step to bring apple juice in line with the current drinking water limits," said Urvashi Rangan, the group's director for consumer safety.

While the Environmental Protection Agency sets arsenic limits for drinking water, there have never been similar standards for most foods and beverages. The FDA is also considering new limits on arsenic in rice, which is thought to have higher levels than most foods because it is grown in water on the ground, optimal conditions for absorbing the contaminant.

"We don't have standards like this in most foods, so it's an important precedent," Rangan said.

Environmental groups like Food and Water Watch have also lobbied the FDA on the issue. And television's Dr. Mehmet Oz made arsenic a national issue in 2011 when he raised an alarm ? some say a false alarm ? over apple juice, based on tests his show commissioned by a private lab.

All of the experts ? including the government and the consumer advocates ? agree that drinking small amounts of apple juice isn't harmful. The concern involves the effects of drinking large amounts of juice over long periods of time.

Another point of agreement is that children under 6 shouldn't be drinking much juice anyway, because it's high in calories. Health experts say children under 6 shouldn't drink any more than 6 ounces of juice a day ? about the size of a juice box. Infants under 6 months shouldn't drink any juice at all.

The American Academy of Pediatrics said Friday children should be encouraged to eat whole fruit adding, "it is not necessary to offer children any juice to have a well-balanced, healthy diet."

____

AP Writer Mary Clare Jalonick contributed to this story.

Source: http://news.yahoo.com/fda-sets-limits-arsenic-apple-juice-040926688.html

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Nick Lachey's Son Has 'A Flair For The Dramatic' Like Mom

Lachey opens up to MTV News about baby Camden and how being a dad is the 'most incredible experience.'
By Jocelyn Vena

Source: http://www.mtv.com/news/articles/1710310/nick-lachey-fatherhood.jhtml

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Video: Bernanke: 'More Needs to be Done'

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Source: http://www.nbcnews.com/video/cnbc/52443772/

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